Wednesday, 11 June




Welcome Address

Gennaro Ciliberto and Alessandro Quattrone

Session I

Molecular trafficking

Chair: Gennaro Ciliberto (Naples)


Marino Zerial (Dresden, Germany)

Multi-scale analysis of cell and tissue organization


Coffee Break


Poster talk: Giovanni Sorrentino (Trieste)

Metabolic control of YAP and TAZ by the mevalonate pathway


Maria Carmo-Fonseca (Lisbon, Portugal)

The timing of pre-mRNA splicing visualized in real-time


Poster talk: Thomas Vaccari (Milan)

Multiple functions of the SNARE protein Snap29 in membrane trafficking during epithelial formation in Drosophila


Roberto Sitia (Milan)

Integrating protein transport, quality control and signaling at the ER Golgi interface


Poster Session I (odd numbers) & Wine and cheese

Thursday, 12 June

Session II

Chromatin plasticity, transcription and translational control

Chairs: Valeria Poli (Turin), Davide Corona (Palermo)


Poster talk: Maria Cristina Onorati (Palermo)

Chromatin remodelers, nucleoplasm compartment and proteinopathies


Poster talk: Graziano Martello (Padua)

Cracking the naive Pluripotency code


Irene Bozzoni (Rome)

Regulatory circuitries controlled by long non coding RNAs


Epigen Special Lecture

Natalia Soshnikova (Mainz, Germany)

Defining stem cell populations in the embryonic gut epithelium


Coffee Break


Stefano Biffo (Milan)

Interactions between translational control and chromatin remodelling


Gunter Meister (Regensburg, Germany)

Regulation of microRNA biogenesis and function


Poster talk: Ian Bonapace (Busto Arsizio)

The epithelial to mesenchymal transition (EMT) induced by cancer associate fibroblasts in PC3 prostate cancer cells generates DNA hypo- and hyper-methylation in different sets of genes by regulating DNMTs and UHRF1 expression levels, which are reverted during mesenchymal to epithelial transition (MET)


Sponsor talks


Lunch Break

Session III

Molecular biology for personalized medicine

Chairs: Andrea Mattevi (Pavia), Caterina Missero (Naples)


Poster talk: Alessandro Romanel (Trento)

Tumor clone dynamics in lethal prostate cancer


Poster talk: Christine Voellenkle (Milan)

Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel non coding RNAs


Francesca Ciccarelli (London, UK)

Systems biology to identify novel anti-cancer therapeutic targets


Giulio Superti-Furga (Vienna, Austria)

OMICS and Drug Action


Poster Session II (even numbers) & Coffee Break


Science Policy

Michele Garfinkel (EMBO)

Policy options for conducting, reporting, and assessing science


General SIBBM Society meeting
(SIBBM members only)


"Notte al Muse" - Dinner and visit

Friday, 13 June

Session IV

Molecular Medicine: towards therapy

Chairs: Michela Denti, Anna Cereseto (Trento)


Poster talk: Lorena Quirico (Turin)

MiR-214 and miR-148b: a miRNA network controlling melanoma progression


Mauro Giacca (Trieste)

Steps towards cardiac muscle regeneration


Fulvio Mavilio (Evry, France)

Gene therapy of monogenic diseases


Coffee Break


Armenise Talk: Tiziana Bonaldi (Milan)

Quantitative proteomics to investigate microRNAs: miR-17-92 counterbalances MYC and fine-tunes MYC-centered regulatory networks to sustain tumor growth


Poster talk: Carla Esposito (Naples)

Development of a combined strategy for selective targeting of glioma by aptamer-miRNA/antimiR chimeras


Poster talk: Giulia Felician (Trieste)

AAV6-mediated reactivation of Notch pathway after myocardial infarction fails to induce cardiac regeneration in adult mice


Chiara D'Onofrio "Giovani" Award
(prize to be awarded to the best Selected Talk)
Poster Prize
Final Remarks & Departure


Posters with an odd number are presented during Poster Session I (Wednesday, 11 June). Posters with an even number are presented during Poster Session II (Thursday, 12 June).

The poster's maximum size is 85cm x 145cm (width x height).

P.1 Anita Annese (Bari)
MiRNA profiling in Alzheimer’s disease by next-generation sequencing
P.2 Laura Bavagnoli (Pavia)
The different substrate specificities of human influenza virus PA, PA-X 61-codon and PA-X 41-codon endonucleases support distinct roles in the viral life cycle
P.3 Federica Bertoletti (Pavia)
Cross-talk of classic and alternative NHEJ repair of DNA breaks in cancer cells
P.4 Francesca Bortolotti (Trieste)
An in vivo selection strategy for the identification of novel cytokines inducing cardiac retention of mesenchymal stem cells after ischemic damage
P.5 Laura Caberlotto (Rovereto)
A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy
P.6 Sonia Caccia (Segrate)
Remittent C1-Inhibitor deficiency due to Arg378Cys mutation
P.7 Antonio Casini (Mattarello (TN))
Identification of nucleoporins involved in HIV-1 integration site selection and provirus localization
P.8 Morena Catillo (Pavia)
Metabolic stress controls alternative splicing programs: relevance to cancer biology
P.9 Emanuela Chiarella (Catanzaro)
UMG-Lenti: novel dual-promoter lentiviral vectors that ensure efficient transgene- and reporter protein expression in human hematopoietic stem and progenitor cells
P.10 Emanuela Chiarella (Catanzaro)
Abundant expression of zinc finger protein 521 (ZNF521) in AMLs correlates with specific genetic aberrations and contributes to the leukaemic phenotype in AMLs with MLL rearrangements
P.11 Lucia Cicchillitti (Rome)
Identification of a novel NF-Y protein partner: characterization of NF-YA/LMNA nuclear complex
P.12 Yari Ciribilli (Mattarello (TN))
Combined TNFα and Doxorubicin treatment of MCF7 cells uncovers cooperative interactions between p53 and NFκB resulting in enhanced cell plasticity
P.13 Tiziana Coradin (Mattarello (TN))
Identification of UBC12 as a new cofactor of HIV-1 integrase
P.14 Davide Corona (Palermo)
Role of the Chromatin RemodelIing  Factor ISWI in Tissue Regeneration
P.15 Alice Cortesi (Milan)
D4Z4 repeat regulates transcription mediating 3D interactions in the genome: biological and pathological implications
P.16 Giuseppina Covello (Mattarello)
Antisense RNA-induced exon-skipping for the gene therapy of Frontotemporal Dementia and Parkinsonism associated with chromosome 17 (FTPD-17)
P.17 Annalisa Crudele (Rome)
Role of LITAF during normal and neoplastic hepatocyte proliferation
P.18 Vito D'Agostino (Mattarello (TN))
FK866 induces cap-dependent translation arrest via AMPK activation in leukemia cells
P.19 Maria Chiara De Santis (Turin)
Loss of PI3KC2α promotes tumorigenesis and aneuploidy in breast cancer
P.20 Valerio Del Vescovo (Trento)
mir-375 and mir-192 expression levels distinguish neuroendocrine from non-neuroendocrine tumors. Novel biomarkers from resected samples
P.21 Emanuela Fanigliulo (Siena)
The adaptor protein Rai: a novel player in multiple sclerosis pathogenesis
P.22 Giulio Ferrero (Orbassano)
Exploration of hormone-independent Estrogen Receptor α activity by integrative and comparative approaches
P.23 Piera Ferro (Fisciano (SA))
Modulation of TFF1 expression in physiological and pathological conditions
P.24 Stephen Findlay-Wilson (Trento)
Development of a fluorescent imaging model for determining the cellular and viral factors influencing HIV-1 infectivity
P.25 Francesca Fontana (Mattarello (TN))
Mechanisms of post-trascriptional regulation of gene expression in dementia
P.26 Mattia Forneris (Turin)
A functional strategy to characterize Quantitative Trait Loci
P.27 Giacomo Frati (Milan)
Patient-specific induced pluripotent stem cells (iPSCs) as a human-derived model to study metachromatic and globoid cell leukodystrophy
P.28 Caterina Gabriele (Catanzaro)
Prostate cancer biomarker discovery on  tissue and serum samples by N-linked glycoprotein profiling and high resolution mass spectrometry
P.29 Maria Nicola Gadaleta (Bari)
Acetyl-L-carnitine chronic treatment to old rat increases biogenesis, turnover and antioxidant defenses in brain mitochondria whereas it reduces oxidized PRXs and the mtDNA4834 mutation content
P.30 Angela Gallo (Rome)
Oligophrenin-1 (OPHN1), a gene involved in X-Linked Intellectual Disability, undergoes RNA editing and alternative splicing during human brain development
P.31 Sonia Iolanda Garritano (Mattarello (TN))
In-silico identification of enhancers bound by androgen receptor reveals allele dependent activity
P.32 Martina Giannaccini (Pisa)
Drug delivery to retinal pigmented epithelium via magnetic nanoparticles
P.34 Francis Kobia (Milan)
Pharmacologic inhibition of vacuolar H+ ATPase (V-ATPase) reduces physiologic and oncogenic Notch signaling
P.35 Mario Lauria (Rovereto)
Rank-based miRNA signatures as biomarkers for neuropsychiatric disorders
P.36 Paola Lecca (Povo (TN))
A reverse engineering gene interaction method and application to prostate cancer molecular sub-classes
P.37 Nadia Lobello (Catanzaro)
Regulation of Stearoyl-CoA desaturase-1 (SCD1), a key factor for propagation and survival of lung cancer stem cells
P.38 Pamela Lorenzi (Verona)
RBM20 role in FHOD3 alternative splicing regulation
P.39 Filippo Macchi (Busto Arsizio)
The role of UHRF1 in CDH1 epigenetic regulation via promoter associated non-coding RNAs
P.40 Monica Mancini (Busto Arsizio)
Carcinogen–induced epigenetic switching in human retroelements: a mechanistic study on hydroquinone effects
P.41 Laura Martini (Mattarello)
In vitro evolution of new RNA sensors
P.42 Michela Masè (Povo (TN))
Structural substrate of atrial fibrillation investigated by miRNAs profiling and histological assessment in cardiac surgery patients
P.43 Valentina Miano (Colleretto Giacosa (TO))
Estrogen Receptor α regulated lncRNAs as new players in maintenance of breast cancer cells phenotype
P.44 Enrico Moiso (Turin)
Overexpression of the muscle specific chaperone Melusin delays heart failure and mortality in a mouse model of Emery Dreyfus cardiomyopathy
P.45 Emanuele Monteleone (Turin)
Potential role of Stat3 in controlling pluripotency and differentiation via lincRNAs transcriptional regulation
P.46 Rosa Montone (Verona)
SADDAN-FGFR3 signalling involves paxillin phosphorylation and causes cytoskeleton disorganization
P.47 Nicoletta Nuzziello (Bari)
sCLU as potential biomarker for the thyroid tumour 
P.48 Nadia Panera (Rome)
Toll like receptor-(TLR) 4 and its downstream lipolysaccharide (LPS)-induced TNF-α factor (LITAF) during nonalcoholic fatty liver disease
P.49 Ilaria Panzeri (Milan)
LincRNAs landscape in human lymphocytes highlights regulation of T cell differentiation by linc-MAF-4
P.50 Elvira Parrotta (Catanzaro)
Understanding the role of mutated BRCA1 on cardiac homeostasis in human iPS-derived cardiomyocytes
P.51 Marsha Pellegrino (Rome)
MDM4/MDM2 association: a new potential therapeutic target for the activation of p53 oncosuppressive function
P.52 Elisa Penna (Turin)
MiR-214 promotes melanoma progression by controlling tumor-endothelial cell interactions during extravasation via ALCAM
P.53 Gianluca Petris (Mattarello (TN))
Distinct requirements of VCP/p97 ATPase and YOD1 activities in ERAD
P.54 Giulia Piaggio (Rome)
In vivo molecular imaging during mammary tumor progression to identify new biomarkers useful for clinical applications
P.55 Cristina Pirrone (Varese)
Molecular detection of BCR-ABL1 genomic breakpoint for the molecular monitoring of residual diseased in chronic myeloid leukemia
P.56 Marta Piscitelli (Milan)
Spera-Experiment to Cure : reasons of research
P.57 Cristina Potrich (Povo (TN))
OncomiR detection in extracellular fluids: a PDMS microdevice perspective
P.58 Vittoria Raffa (Pisa)
Magnetic nanoparticles can direct axonal growth
P.59 Mauro Rassu (Sassari)
Role of LRRK2 in the regulation of dopamine receptor trafficking
P.60 Stefania Reineri (Colleretto Giacosa)
Estrogen regulates neuroglobin transcription in neuronal and non-neuronal cancer cells
P.61 Riccardo Ronzoni (Brescia)
Aberrant disulphide interactions contribute to the secretory deficiency of Alpha 1-Antitrypsin mutants
P.62 Annalisa Rossi (Trento)
Functional characterization of Raly a new member of RNA-binding protein containing ribonucleoparticles family
P.63 Maria Elisabetta Ruaro (Udine)
Development of new tools to define prognosis and patient-tailored therapeutic strategies for low-grade glioma patients
P.64 Stefania Scicchitano (Catanzaro)
Critical role of zinc finger protein 521 in the regulation of growth and tumourigenic potential of human medulloblastoma cells
P.65 Kavitha Siva (Trento)
Could RNAi be a therapeutic approach for Fronto Temporal Dementia and Parkinsonism linked to chromosome 17?
P.66 Letizia Straniero (Milan)
Exploring the role of a ceRNA-based regulatory network, involving GBA and GBAP1, in Parkinson disease
P.67 Alessandro Testori (Turin)
Transcriptome evolution via transposable elements
P.68 Mariaconcetta Varano (Catanzaro)
Whole proteome and main Post-translational modifications (PTMs) analysis of K. pneumoniae clinical isolates
P.69 Laura Vidalino (Trento)
Dynamic association with the nucleoli of C14orf21, a novel PUF-containing RNA-binding protein in mammals
P.70 Valeria Visone (Naples)
A new analytical approach to study DNA protein interactions and modifications
P.71 Germana Zaccagnini (San Donato Milanese, Milan)
microRNA-210: a master miRNA of the hypoxia response
P.72 Melania Zanchetta (Trieste)
MID1/TRIM18 interacts with BRAF35 and regulates its ubiquitination
P.73 Elisa Zucca (Pavia)
Interplay of DNA polymerase λ, protection of telomeres (Pot) 1 and TERRA in telomere elongation
P.74 Paola Zuccotti (Trento)
Mapping HuD interactom by cross-linking and sequencing of  hybrids


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